Focal Segmental Glomerulosclerosis (FSGS) - The National Kidney Foundation
INTRODUCTION. Focal segmental glomerulosclerosis (FSGS) is a morphologic pattern of glomerular injury primarily directed at the glomerular visceral epithelial cell (the podocyte) and defined by the presence of sclerosis in parts (segmental) of some (focal) glomeruli by light microscopy of a kidney biopsy specimen.
Focal segmental glomerulosclerosis (FSGS) - Symptoms and causes
FSGS is a rare disease that attacks the kidney's filtering units (glomeruli) and causes serious scarring, leading to permanent kidney damage and even kidney failure. FSGS is one of the causes of a serious condition known as Nephrotic Syndrome. Overview and symptoms.
Focal Segmental Glomerulosclerosis - StatPearls - NCBI Bookshelf
Focal segmental glomerulosclerosis (FSGS) is a leading cause of kidney disease worldwide. The presumed etiology of primary FSGS is a plasma factor with responsiveness to immunosuppressive therapy and a risk of recurrence after kidney transplant-important disease characteristics.
Focal segmental glomerulosclerosis - Wikipedia
FSGS is a chronic condition that damages the glomeruli, the filtering units inside the kidneys. It can cause scarring, swelling, protein loss, and kidney failure. Learn about the symptoms, causes, diagnosis, and treatment of FSGS from this article.
Focal Segmental Glomerulosclerosis (FSGS) - Cleveland Clinic
Focal segmental glomerulosclerosis (FSGS) is a serious condition leading to kidney failure. We aimed to investigate the clinical characteristics of FSGS and its differences compared with...
Focal Segmental Glomerulosclerosis (FSGS) | UNC Kidney Center
Analysis of the first 72 randomized patients with FSGS indicated that DMX-200 had performed better than the placebo in reducing proteinuria, a high level of protein in urine that is a marker of kidney disease progression. Dimerix Chief Medical Officer Dr. David Fuller said passing this first interim analysis for DMX-200 was a key milestone.
Focal Segmental Glomerulosclerosis: Symptoms and Treatment - Healthline
FSGS is a kidney condition that affects, initially some ('focal') and part of ('segmental'), glomeruli, which are the tiny filters inside the nephrons in the kidney. In FSGS, scarring (medically called 'sclerosis') develops on small sections of each glomerulus (filter) and this affects the ability of the kidneys to work as they should.
How does FSGS affect the kidneys? Symptoms and treatment
Focal segmental glomerulosclerosis (FSGS) is a diagnosis based on the presence of glomeruli with segmental scarring in association with intracapillary foam cells and adhesions. To develop evidence-based treatment guidelines, a MEDLINE search was conducted, and articles were reviewed using levels of evidence.
Focal segmental glomerulosclerosis: Treatment and prognosis
FSGS is a chronic condition that affects the filters of the kidneys and can lead to kidney failure. Learn about the symptoms, causes, types, diagnosis and treatment of FSGS from Kidney Fund, a nonprofit organization that supports kidney patients.
Focal segmental glomerulosclerosis (FSGS) - American Kidney Fund
Focal and segmental glomerulosclerosis (FSGS) is a medical term for a family of diseases involving damage to the glomeruli (the tiny filters in the kidney). The damage causes scarring to the filters which then stop working properly. This allows protein to leak through the walls of the glomeruli and into the urine.